منابع مشابه
Metabolism of drugs. LXXX. The metabolic fate of nitrofuran derivatives. 3. Studies on enzymes in small intestinal mucosa of rat catalyzing degradation of nitrofuran derivatives.
The enzymes responsible for the degradation of nitrofuran derivatives in rat small intestinal mucosa were examined in vitro.As a result,it was suggested that the initial reactions in the degradation of 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide(AF-2) and 5-nitro-2-furfural semicarbazone(nitrofurazone)are mainly catalyzed by xanthine oxidase , while that of 2-amino-5-[2-(5-nitro-2-fury1)-1-(2-fur...
متن کاملInduction of unscheduled DNA synthesis in primary culture of dog, rat, and mouse urothelial cells by arylamine and nitrofuran derivatives.
The induction of unscheduled DNA synthesis in primary cultures of urothelial cells from rats, mice, and dogs by nitrofurans and arylamines and their derivatives was examined. Electron microscopy of the culture from rat cells showed the characteristics of epithelial cells. The cultured cells were exposed to the test chemicals in a serum-free medium containing 10 mM hydroxyurea and [3H]thymidine ...
متن کاملSynthesis, Characterization and in Vitro Antimicrobial Screening of the Xanthate Derivatives and their Iron(II) Complexes
Seven reported xanthate ligands and their new Fe(II) complexes of formulaNa[Fe(R-OCSS)3], where R is ethyl-, propyl-, butyl-, pentyl-, Hexyl-, heptyl- and octyl-xanthate have been synthesized. They have been characterized using elemental analysis, molar conductance, FT-IR, UV-Vis and 1H NMR spectroscopic techniques and melting-, decomposition-points for ligand...
متن کاملMn(II), Ni(II), and Cu(II) Complexes of Artmisinin Derivatives: Synthesis, Characterization and Antimicrobial Activities
A range of transition metals ligated by sesquiterpene lactone-artesunate (ATS) have been investigated. Syntheses of Cu(II), Ni(II), and Mn(II) complexes of decahydro-3,6,9-trimethyl3,12-epoxy-12H-pyrano[4,3-j]1,2-benzodioxepin10-ol hydrogen succinate were prepared by a direct aqueous substitution reaction in methanol. Structural elucidations of the complexes were determined using X-Ray Diffract...
متن کاملEffiecient Synthesis of tetrazoloquinoxaline derivatives
Displacement reaction of 2,3-dichloroquinoxaline with secondary amines in boiling ethanol afforded it`s mono aminoquinoxaline derivatives. Further reaction of the latter compounds with sodium azide in warm dimethylsulfoxide achieved a group of 4-amino tetrazolo[1,5-a]quinoxaline derivatives. 1HNMR spectra of these compounds are discussed.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1965
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.85.5_424